Andy Robinson has selected three uncapped players in his squad for his first Test in charge of Scotland, against Fiji at Murrayfield next month.
MacDonald, Vernon and Grove were all members of the IRB Nations Cup-winning Scotland A team that Robinson took to Romania in June.
A former England back-row himself, Robinson praised MacDonald and Vernon by saying: "Both have done well this season where, once again, the competition in the back-row is intense with Roddy Grant also knocking on the door."
Meanwhile Robinson insisted the door had not been closed on the likes of Glasgow No 10 Parks and that players could force their way in for Scotland's other Tests next month, against Australia on November 21 and Argentina on November 28.
The squad will gather for a three-day camp on November 2 then reconvene at Murrayfield on November 8 ahead of the Fiji match on November 14.
Robinson, 45, who had spent the last two seasons with Edinburgh after an unsuccessful spell in charge of England, returned to international rugby union in June as the successor to Frank Hadden, who stepped down as Scotland coach after this year's Six Nations.
His main task, having been given a three-year contract, is to improve Scotland's standing in the Six Nations, with Hadden having overseen just one win in each of the last three championships.
Robinson's reputation was badly damaged by his two years in charge of England, during which the then world champions won just nine out of 22 Tests.
But he has enjoyed success either side of that unhappy spell.
A former Bath and England flanker, he led the English club to European Cup glory in 1998 and was credited with playing a key role in England's 2003 World Cup win, when he served as forwards coach under Clive Woodward.
Since taking over at Edinburgh in 2007, he has twice led them to their highest-ever Celtic League finish - including last season's second place.
Scotland squad for the rugby union international against Fiji at Murrayfield on November 14:
Mike Blair (Edinburgh), Ben Cairns (Edinburgh), Chris Cusiter (Glasgow), Simon Danielli (Ulster/IRL), Nick de Luca (Edinburgh), Thom Evans (Glasgow), Phil Godman (Edinburgh), Alex Grove (Worcester/ENG), Rory Lamont (Toulon/FRA), Sean Lamont (Scarlets/WAL), Rory Lawson (Gloucester/ENG), Scott Lawson (Gloucester/ENG), Graeme Morrison (Glasgow), Chris Paterson (Edinburgh), Hugo Southwell (Stade Francais/FRA), Nikki Walker (Ospreys/WAL)
John Barclay (Glasgow), Johnnie Beattie (Glasgow), Kelly Brown (Glasgow), Geoff Cross (Edinburgh), Alasdair Dickinson (Gloucester/ENG), Ross Ford (Edinburgh), Dougie Hall (Glasgow), Nathan Hines (Leinster/IRL), Allan Jacobsen (Edinburgh), Alastair Kellock (Glasgow), Moray Low (Glasgow), Alan MacDonald (Edinburgh), Scott MacLeod (Edinburgh), Alasdair Strokosch (Gloucester/ENG), Richie Vernon (Glasgow), Jason White (Clermont Auvergne/FRA)
Source: AFP Global Edition