Earlier in the week, Chicago Blackhawks agitator Dave Bolland in a radio interview referred to the Swedish twins as the Sedin "sisters," prompting an angry retort from Vancouver coach Alain Vigneault.
The Sedins had little to say.
The barbs are nothing new for the identical twins and they responded way they always have -- Daniel scoring late in the second period to give the Canucks a lead they would not surrender and Henrik setting up Alex Burrows third period game winner.
"We're 3-1-1, that's a pretty good road trip, we're really happy with that," Daniel told reporters after notching his 13th goals of the season.
"We are a good road team and we showed that. It doesn't matter what the score is we play the same way, if we are down or we are up.
"We keep things going, we try to make them break and they did tonight."
The Leafs have no particular beef with the Sedins other than being unable to beat the Canucks, who have now won 10 straight over Toronto going back to November 2003.
Both have won Art Ross trophies as the NHL's leading scorer, Henrik in 2010 and Daniel in 2011.
Henrik was also awarded the Hart trophy as the league's most valuable player in 2010 while Daniel was a finalist last year.
The twins came into Saturday's game in the top 10 of league scoring and added to their totals against the falling Leafs, who have now lost four of their last five.
The Canucks were out of the gate quickly, Chris Higgins flipping a backhand over Toronto's Swedish netminder Jonas Gustavsson just 62 seconds after the opening faceoff but the Leafs answered with a powerplay goal from Joffrey Lupul.
With 44 seconds remaining in the period, Daniel Sedin put the Canucks ahead to stay taking a perfect feed from Burrows and redirecting it over a helpless Gustavsson's shoulder.
Burrows then added an insurance marker late in the final period by ricocheting a shot off the post to put the visitors up 4-2.
"Ever since I came into the league the Leafs are a team I hated as a kid," said Burrows. "I grew up in Montreal and when you are a Habs fan it seems it is just in your blood (to hate the Leafs).
"I know a lot of fans in Vancouver don't like this team it just makes it extra-special (to get a win)."
(Reporting by Steve Keating in Toronto)