Zoladex
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Zytiga creeps up on Provenge prostate-cancer drug
Oct 07, 2011 15:19 EDT
NEW YORK (Reuters) - Interest in Dendreon Corp's Provenge vaccine to treat prostate cancer seems to be waning following recent approval of Johnson & Johnson's more-convenient and faster-acting Zytiga treatment, according to some doctors and industry analysts.
Prostate cancer treatment may be tied to cataracts
Dec 27, 2010 13:44 EST
NEW YORK (Reuters Health) - Older men who opt for hormone-blocking therapy to treat prostate cancer might be slightly raising their risk of developing cataracts, hints new research.
Prostate Cancer Treatment May Up Colon Cancer Risk
Nov 12, 2010 12:46 EST
NEW YORK (Reuters Health) - Men who opt for hormone-blocking therapy to treat prostate cancer may be increasing their risk of developing colon cancer, hints a study published this week in the Journal of the National Cancer Institute.
Prostate cancer treatment may up colon cancer risk
Nov 12, 2010 12:20 EST
NEW YORK (Reuters Health) - Men who opt for hormone-blocking therapy to treat prostate cancer may be increasing their risk of developing colon cancer, hints a study published this week in the Journal of the National Cancer Institute.
AstraZeneca Q3 profit down 27 pct amid legal costs
Oct 28, 2010 08:11 EDT
Pharmaceutical company AstraZeneca on Thursday reported a 27 percent drop in third-quarter profit as it set aside nearly half a billion dollars to settle claims that its anti-psychotic drug Seroquel has harmful side-effects.
FDA warns of prostate cancer drug risks
Oct 20, 2010 20:45 EDT
WASHINGTON (Reuters) - Hormone treatments for prostate cancer need new warnings about a small increased risk of diabetes and heart problems including sudden death, U.S. health officials said on Wednesday.
U.S. reviews diabetes, heart risk with prostate drugs
May 03, 2010 17:19 EDT
WASHINGTON (Reuters) - The U.S. Food and Drug Administration is examining if certain hormone treatments for men with prostate cancer pose a greater risk of diabetes or heart problems than other therapies.
FDA probes diabetes risk with prostate cancer meds
May 03, 2010 13:20 EDT
The Food and Drug Administration is looking into data suggesting a group of prostate cancer drugs increase the risk of diabetes and heart disease.
FDA probes diabetes risk with prostate cancer meds
May 03, 2010 13:19 EDT
FDA warns that early evidence shows links between prostate cancer drugs and diabetes. The Food and Drug Administration is looking into data suggesting a group of prostate cancer drugs increase the risk of diabetes and heart disease.
AstraZeneca loses price inflation lawsuit appeal
Sep 24, 2009 14:54 EDT
AstraZeneca loses appeal over drug wholesale price inflation lawsuit in Massachusetts. An appeals court on Wednesday upheld a lower court's ruling that AstraZeneca inflated the price of expensive drugs in Massachusetts.
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Facts from the Wikipedia page:
| Systematic (IUPAC) name | |
|---|---|
| N-[1-[[1-[[1-[[1-[[1-[[1-[[1-[2- [(carbamoylamino)carbamoyl]pyrrolidin-1-yl]- 5-(diaminomethylideneamino)-1-oxo -pentan-2-yl]carbamoyl]-3-methyl- butyl]carbamoyl]-2-tert-butoxy- ethyl]carbamoyl]-2-(4-hydroxyphenyl) ethyl]carbamoyl]-2-hydroxy-ethyl] carbamoyl]-2-(1H-indol-3-yl)ethyl] carbamoyl]-2-(3H-imidazol-4-yl)ethyl]- 5-oxo-pyrrolidine-2-carboxamide | |
| Identifiers | |
| CAS number | 65807-02-5 |
| ATC code | L02AE03 |
| PubChem | 47725 |
| DrugBank | BTD00113 |
| Chemical data | |
| Formula | C59H84N18O14 |
| Mol. mass | 1269.410 g/mol |
| Synonyms | D-Ser(But)6Azgly10LHRH |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | 27.3% |
| Metabolism | ? |
| Half life | 4-5 hours |
| Excretion | renal |
| Therapeutic considerations | |
| Pregnancy cat. |
D (3.6mg) / X (10.8mg) (USA) |
| Legal status |
℞ Prescription only |
| Routes | implant
|